Whitening Efficacy — Human Clinical Trial (28-Day)
Study at a glance
- CAIQ Cosmetics Technology Center, Chinese Academy of Inspection and Quarantine
- Institution
- Project No.: 2024-287-KQ-143
- Single-center, 4-week oral test, twice daily (morning & evening)
- Design
- 32 qualified participants, 0 dropouts
- Subjects
- Report Date: September 26, 2024
- GCP principles & Declaration of Helsinki
- Ethics
Conclusion
After 4 weeks of combined use, the products effectively removed exogenous pigments, reduced tooth yellowness, and improved whiteness and color uniformity. All oral tissues remained normal and no adverse reactions were reported, demonstrating excellent safety.
Evaluation Methods
- Lobene Stain Score
- plaque and extrinsic stain index
- VITA Shade Guide
- tooth color assessment
- Oral Soft & Hard Tissue Evaluation
- safety assessment by dental professionals
- VITA Easyshade
- tooth whiteness index (WIO), b*, ITA°
- Image-Pro Plus
- image analysis for color uniformity
- Questionnaire
- user satisfaction & experience survey
User Satisfaction (Week 4)
| Dimension | Satisfaction |
|---|---|
| Teeth whitening effect | 100% |
| Stain removal effect | 100% |
| Teeth brightening effect | 100% |
| Teeth yellowing reduction | 100% |
| Teeth cleaning effect | 100% |
| Breath freshening | 100% |
| No tooth sensitivity or pain | 100% |
| No adverse reactions | 100% |
| Overall experience | 100% |
Download reports
- 28-Day Human Clinical Trial ReportENPDF · 2.4mDownload